From the category archives:

Tamiflu

Tamiflu – stops the flu but makes you sick?

A total of 171 campers, 48 camp counsellors and 27 camp staff were involved. Three campers tested positive for H1N1 during one of the camp’s two-week sessions. These received oseltamivir and were immediately isolated and sent home. All campers and counsellors in the infected child’s adjoining cabins took oseltamivir prophylactically for 10 days. In addition, [...]

Read the full article →

Resistance to Tamiflu – The Science

Analysis of a phylogenetic tree for NAs in seasonal H1N1 viruses from 2006 and later led to identification of two candidate mutations (V234M and R222Q) that could have permitted the occurrence of the H274Y mutation without substantial loss of viral fitness among naturally circulating viruses. Additional studies verified that both of these mutations restored both [...]

Read the full article →

H1N1 virus has mutated

The H1N1 virus has undergone a slight genetic mutation and its effect on patients has also changed. But patients are still responding to anti-viral drug Tamiflu. “Unlike last year, swine flu patients don’t have high fever these days. Severe sore throat and backache are the most prominent symptoms now,” said Dr G.T. Ambe, Brihanmumbai Municipal [...]

Read the full article →

Tamiflu resistant cluster in Slovenia

Long-term care facilities are vulnerable to outbreaks of influenza. This report describes the response to such an outbreak in a long-term care facility for severely handicapped children and adults near Ljubljana, Slovenia, in March and April 2009. Of the 23 residents who lived in a unit of the facility, 10 fell ill with fever (≥37.5 [...]

Read the full article →

Community Transmission of pH1N1 Tamiflu Resistance In Israel

n November 2009, a healthy 2-year-old boy was admitted to the pediatric intensive care unit at the Western Galilee Hospital in Nahariya, Israel, after he had been hit by a car. One day before the accident, he had exhibited fever and cough (for which he had been treated with acetaminoiphen). His 4-year-old brother had recovered [...]

Read the full article →

Triple Combination Anti Flu Drug Being Trialled

The study conducted by investigators at the Fred Hutchinson Cancer Research Center in Seattle, Washington, and Seattle Children's Hospital, was a randomized, open-label study of TCAD therapy (amantadine and ribavirin administered with oseltamivir) versus oseltamivir monotherapy in immunocompromised patients with Influenza A. The objective of the study was to assess the safety, tolerability, and virologic [...]

Read the full article →

Widespread pH1N1 Tamiflu Resistance In South Korea

The CDC in South Korea has released 16 pH1N1 NA sequences at Genbank and 10 had H274Y. Although multiple samples appear to have been collected from two patients, more than half of the patients had H274Y, including the two infected in 2010. This increase of H274Y in recent cases is similar to data released by [...]

Read the full article →

Flu drugs saved many pregnant swine flu victims

Quick treatment with flu medicine saved the lives of many pregnant women who were stricken by swine flu last year, according to the most complete analysis of deaths among expectant mothers. The study by the Centers for Disease Control and Prevention counted 56 pregnant women who died from the new virus in 2009, confirming the [...]

Read the full article →

Tamiflu Monotherapy Remains the Best For Flu

Monotherapy with oseltamivir shows greater efficacy than its combination with zanamivir, and than zanamivir alone, in patients with seasonal influenza, according to a study presented here at the 20th European Congress of Clinical Microbiology and Infectious Diseases ECCMID. via News – Oseltamivir Monotherapy Remains the Best First-Line Antiviral Strategy for Influenza: Presented at ECCMID.

Read the full article →

Tamiflu resistant swine flu warning to cancer patients

Health experts have issued a warning to people with certain medical conditions and their carers after it emerged that a number of Scots are suffering from so-called super swine flu. They have called for patients with compromised immune systems – primarily cancer sufferers – to ensure they are vaccinated against swine flu after nine people [...]

Read the full article →

← Previous Entries